Real Problems · Real Science

Your body, understood.

Eight everyday concerns — each broken down into how it shows up in daily life, the exact ingredients inside Floradyle that help, and what the clinical studies show.

Low Energy & Fatigue

Cells run out of ATP — the fuel your body actually burns.

How it affects your life

Afternoon crashes, brain fog and constant tiredness
Reliance on coffee and sugar just to get through the day
Workouts feel heavier, recovery takes longer
Motivation drops, focus slips at work and home

How Floradyle helps

Fuels mitochondria so cells produce more ATP naturally
Clinical study: ATP levels rose +122% in 6 months (n=31)
Participants reported +60% physical fitness, +59% focus
Steady, jitter-free vitality — no caffeine spike or crash

Mechanism of action

Cascade-fermented enzyme precursors feed the mitochondrial respiratory chain.
Improved cytochrome c oxidase activity restores oxidative phosphorylation.
Effect persists after stopping intake — a sign of true mitochondrial repair, not stimulation.

Clinical evidence

Granulocyte ATP study, chronic energy deficit

n = 31 patients · 3–6 months daily intake

Mean intracellular ATP rose 0.68 → 1.51 µM (+122%) at 6 months.
ATP-deficient subgroup: +183% increase in 3 months alone.
Three months after stopping, ATP was still climbing (+187% vs baseline).
Self-reported physical fitness +60%, concentration +59%.

Key ingredients

L(+) Lactic Acid

Cellular energy carrier

+122%

Cellular ATP after 6 months

High Blood Pressure & Heart

Stiff arteries and oxidative stress raise cardiac risk.

How it affects your life

Headaches, fatigue and shortness of breath on stairs
Sedentary days, salty diet, chronic stress at work
Worry about long-term risk of heart attack or stroke
Medication side effects you'd rather avoid

How Floradyle helps

Systolic pressure dropped 131 → 121 mmHg in 6 months
Lowers oxidised LDL — the dangerous form of cholesterol
Helps arteries regain elasticity and clear deposits
Average 4.6 kg weight loss without diet changes

Mechanism of action

Reduces oxidative stress that damages arterial walls and stiffens vessels.
Lowers oxidised LDL — the cholesterol form that actually drives plaque.
Normalises vanillylmandelic acid — a marker of stress-driven sympathetic overdrive.

Clinical evidence

Open-label CAM study, hypertensive & metabolic patients

n = 28 across two cohorts · 6 months daily intake

Systolic BP: 131 → 121 mmHg (study 1); 140 → 124 mmHg (study 2).
Diastolic BP: 74 → 69 mmHg (study 1); 82 → 77 mmHg (study 2).
Mean weight loss of 4.5–4.6 kg without dietary change.
In vitro: LDL oxidation lag delayed 120 → 432 min with Floradyle + vitamin C.

Key ingredients

Polyphenols

Protect vessel walls

−10 mmHg

Mean systolic drop

Diabetes & Metabolic Syndrome

Insulin resistance, belly fat and the 'fatal four'.

How it affects your life

Sugar cravings, energy dips after meals
Belly fat that won't budge despite effort
Rising HbA1c, triglycerides or blood pressure
Family history of type-2 diabetes

How Floradyle helps

Lowers HbA1c, triglycerides and LDL cholesterol
Raises 'good' HDL cholesterol
Reduces uric acid and homocysteine
Mean 4.5 kg weight loss with no diet change
Less appetite for sweets, more energy and focus

Mechanism of action

Enzyme regulation re-tunes glucose, fat, energy and purine metabolism together.
Improves insulin sensitivity — intact pro-insulin and HbA1c fall in tandem.
Anti-inflammatory and antioxidant action interrupts the cycle that drives the 'fatal four'.

Clinical evidence

Two CAM studies in type-2 diabetes & metabolic syndrome

n = 28 (13 + 15) · 6 months daily intake

Mean LDL: 130 → 114 mg/dl; HDL increased.
HbA1c, triglycerides, uric acid and homocysteine all decreased.
Mean weight loss 4.5–4.6 kg with no dietary changes.
Energy +53%, concentration +58%, sweet cravings dropped.

Key ingredients

Cascade Ferment

Restores enzyme balance

−4.5 kg

Average weight loss, 6 months

IBS, Bloating & Gut Health

An unbalanced microbiome inflames the whole body.

How it affects your life

Bloating, cramps and unpredictable bathroom trips
Food sensitivities and post-meal discomfort
Low mood and brain fog (the gut–brain axis)
Travel and stress wreck your digestion

How Floradyle helps

82.5% of IBS patients improved in an 8-week study (n=52)
92% improvement in diarrhoea-dominant IBS
L(+) lactic acid feeds beneficial gut flora
Pre-digested enzymes ease bloating and gas
Calms inflammation in the intestinal mucosa

Mechanism of action

Dextrorotatory L(+) lactic acid feeds beneficial flora and restores colonic pH.
Peptidoglycans from lactobacilli cell walls train gut-associated immunity.
Pre-digested oligopeptides reduce the digestive burden that triggers IBS flares.

Clinical evidence

8-week IBS effectiveness study

n = 52 · 8 weeks daily intake

82.5% of patients reported overall improvement.
92% improvement in diarrhoea-dominant IBS subgroup.
Reductions in abdominal cramping, bloating and stool irregularity.
Improved tolerance to previously triggering foods.

Key ingredients

L(+) Lactic Acid

Healthy gut pH

Lactobacilli

Probiotic cell-wall support

82.5%

of IBS patients improved

Detox, Liver & Acidity

Daily toxin load overwhelms your filter system.

How it affects your life

Sluggish mornings, dull skin, puffy eyes
Heavy meals, alcohol, processed food
Reflux, heartburn or acidic stomach
Environmental toxins from city life

How Floradyle helps

Phenolic acids switch on phase I & II detox enzymes
Artichoke and curcuma support bile flow
Reduces acidosis — the body returns to balance
Heartburn and reflux symptoms ease, often within weeks

Mechanism of action

Phenolic acids (hydroxycinnamic, ellagic) induce phase I & II detox enzymes.
Cynarine from artichokes drives bile flow — the primary route to clear fat-soluble toxins.
Phytochemicals undergo basic (alkaline) metabolism, reversing tissue acidosis at the source.

Clinical evidence

Total Oxidative Status (TOS), randomised intervention

Healthy adults, baseline TOS > 100 µmol/l · 4 weeks daily intake

Floradyle group: TOS dropped −39.5 µmol/l (significant).
Placebo group: TOS dropped only −16.1 µmol/l (not significant).
Greater benefit in those who needed it most — true regulator behaviour.
Intracellular reduced glutathione (master antioxidant) increased significantly.

Key ingredients

Phase I + II

Detox pathways activated

Skin, Eczema & Aging

Inflammation and oxidative stress age skin from within.

How it affects your life

Dry, itchy patches or eczema flare-ups
Dull tone, fine lines, slow recovery from blemishes
Stress and lack of sleep show on your face
You want results without strong steroid creams

How Floradyle helps

In-vitro: matched dexamethasone in calming skin inflammation
Activates proteasomes — clears damaged proteins in skin cells
Raises ATP in keratinocytes for stronger, springier skin
Can be sprayed topically (1:1 water) on affected areas

Mechanism of action

Reduces IL-6 and IP-10 — the inflammatory messengers that drive eczema and redness.
Activates proteasomes that clear damaged proteins inside aged keratinocytes.
Raises ATP in skin cells, restoring division capacity that slows with age.

Clinical evidence

In vitro atopic-dermatitis & anti-ageing models

Skin epithelial cells + activated T lymphocytes · 24–48 h cell-culture exposure

IP-10 reduced to ~8% of control — better than dexamethasone (~50%).
IL-6 reduction comparable to corticosteroid dexamethasone.
Dose-dependent proteasome activation in artificially aged keratinocytes.
Topical 1:1 spray reported to ease eczema, psoriasis and slow-healing wounds.

Key ingredients

Polyphenols

Anti-aging antioxidants

≈ Steroid

Anti-inflammatory power, in vitro

Immunity & Infections

A tired immune system can't tell friend from foe.

How it affects your life

Catching every cold the office passes around
Slow wound healing, lingering skin infections
Allergies, hayfever, food intolerances
Run-down feeling after travel or stress

How Floradyle helps

Activates neutrophils and NK cells (innate defence)
Modulates — not over-stimulates — the immune response
Direct antimicrobial action vs. bacteria & fungi
Raises IL-10 (immune tolerance), no IL-4 spike (no allergy boost)

Mechanism of action

Activates innate defence (neutrophils, NK cells) without over-stimulating adaptive response.
No IL-4 spike — does not provoke atopy or allergy reactions.
Microbial challenge test: direct antimicrobial action against bacteria and fungi.

Clinical evidence

Immunomodulation & microbial challenge

In vitro / ex vivo human cell models · Multiple replicate experiments

IL-10 (immune tolerance) significantly raised.
Probiotic peptidoglycans from lactobacilli cell walls boost mucosal immunity.
Direct kill curves against Candida, S. aureus and other common pathogens.
Reported topical use accelerates wound, abscess and cold-sore healing.

Key ingredients

Lactobacilli

Trains the immune system

NK + Neutrophils

Activated for whole-body defence

Inflammation & Joint Pain

Silent inflammation drives pain, stiffness and aging.

How it affects your life

Morning stiffness, achy knees or shoulders
Slower recovery after exercise or long days
Background pain that paracetamol only masks
You want relief without daily NSAIDs

How Floradyle helps

Reduces IL-6 and IP-10 — key inflammatory messengers
Raises intracellular glutathione (master antioxidant)
Supports joint comfort, mobility and recovery
Reduces oxidative stress most in those who need it most

Mechanism of action

Polyphenols and curcuminoids quiet IL-6 and IP-10 inflammatory cascades.
Raises intracellular glutathione — the master antioxidant cells use to neutralise ROS.
Reduces oxidative stress more in those with the highest baseline — a regulator, not a stimulant.

Clinical evidence

Intracellular glutathione + cytokine panel

Real-life intervention cohort · 6 months daily intake

Pro-inflammatory IL-6 reduced to dexamethasone-comparable levels in vitro.
Reduced glutathione (GSH) significantly raised in cells.
Almost all patients with chronic inflammation reported clear or complete relief of symptoms.
Joint comfort, mobility and post-exertion recovery improved subjectively.

Key ingredients

↓ IL-6

Inflammatory marker reduced

01 / 08

Low Energy & Fatigue

Cells run out of ATP — the fuel your body actually burns.

Mechanism of action

Cascade-fermented enzyme precursors feed the mitochondrial respiratory chain.
Improved cytochrome c oxidase activity restores oxidative phosphorylation.
Effect persists after stopping intake — a sign of true mitochondrial repair, not stimulation.

+122%

Cellular ATP after 6 months

How it affects your life

Afternoon crashes, brain fog and constant tiredness
Reliance on coffee and sugar just to get through the day
Workouts feel heavier, recovery takes longer
Motivation drops, focus slips at work and home

How Floradyle helps

Fuels mitochondria so cells produce more ATP naturally
Clinical study: ATP levels rose +122% in 6 months (n=31)
Participants reported +60% physical fitness, +59% focus
Steady, jitter-free vitality — no caffeine spike or crash

Clinical evidence

Granulocyte ATP study, chronic energy deficit

n = 31 patients· 3–6 months daily intake

Mean intracellular ATP rose 0.68 → 1.51 µM (+122%) at 6 months.
ATP-deficient subgroup: +183% increase in 3 months alone.
Three months after stopping, ATP was still climbing (+187% vs baseline).
Self-reported physical fitness +60%, concentration +59%.

Key ingredients at work

L(+) Lactic Acid

Cellular energy carrier

02 / 08

High Blood Pressure & Heart

Stiff arteries and oxidative stress raise cardiac risk.

Mechanism of action

Reduces oxidative stress that damages arterial walls and stiffens vessels.
Lowers oxidised LDL — the cholesterol form that actually drives plaque.
Normalises vanillylmandelic acid — a marker of stress-driven sympathetic overdrive.

−10 mmHg

Mean systolic drop

How it affects your life

Headaches, fatigue and shortness of breath on stairs
Sedentary days, salty diet, chronic stress at work
Worry about long-term risk of heart attack or stroke
Medication side effects you'd rather avoid

How Floradyle helps

Systolic pressure dropped 131 → 121 mmHg in 6 months
Lowers oxidised LDL — the dangerous form of cholesterol
Helps arteries regain elasticity and clear deposits
Average 4.6 kg weight loss without diet changes

Clinical evidence

Open-label CAM study, hypertensive & metabolic patients

n = 28 across two cohorts· 6 months daily intake

Systolic BP: 131 → 121 mmHg (study 1); 140 → 124 mmHg (study 2).
Diastolic BP: 74 → 69 mmHg (study 1); 82 → 77 mmHg (study 2).
Mean weight loss of 4.5–4.6 kg without dietary change.
In vitro: LDL oxidation lag delayed 120 → 432 min with Floradyle + vitamin C.

Key ingredients at work

Polyphenols

Protect vessel walls

03 / 08

Diabetes & Metabolic Syndrome

Insulin resistance, belly fat and the 'fatal four'.

Mechanism of action

Enzyme regulation re-tunes glucose, fat, energy and purine metabolism together.
Improves insulin sensitivity — intact pro-insulin and HbA1c fall in tandem.
Anti-inflammatory and antioxidant action interrupts the cycle that drives the 'fatal four'.

−4.5 kg

Average weight loss, 6 months

How it affects your life

Sugar cravings, energy dips after meals
Belly fat that won't budge despite effort
Rising HbA1c, triglycerides or blood pressure
Family history of type-2 diabetes

How Floradyle helps

Lowers HbA1c, triglycerides and LDL cholesterol
Raises 'good' HDL cholesterol
Reduces uric acid and homocysteine
Mean 4.5 kg weight loss with no diet change
Less appetite for sweets, more energy and focus

Clinical evidence

Two CAM studies in type-2 diabetes & metabolic syndrome

n = 28 (13 + 15)· 6 months daily intake

Mean LDL: 130 → 114 mg/dl; HDL increased.
HbA1c, triglycerides, uric acid and homocysteine all decreased.
Mean weight loss 4.5–4.6 kg with no dietary changes.
Energy +53%, concentration +58%, sweet cravings dropped.

Key ingredients at work

Cascade Ferment

Restores enzyme balance

04 / 08

IBS, Bloating & Gut Health

An unbalanced microbiome inflames the whole body.

Mechanism of action

Dextrorotatory L(+) lactic acid feeds beneficial flora and restores colonic pH.
Peptidoglycans from lactobacilli cell walls train gut-associated immunity.
Pre-digested oligopeptides reduce the digestive burden that triggers IBS flares.

82.5%

of IBS patients improved

How it affects your life

Bloating, cramps and unpredictable bathroom trips
Food sensitivities and post-meal discomfort
Low mood and brain fog (the gut–brain axis)
Travel and stress wreck your digestion

How Floradyle helps

82.5% of IBS patients improved in an 8-week study (n=52)
92% improvement in diarrhoea-dominant IBS
L(+) lactic acid feeds beneficial gut flora
Pre-digested enzymes ease bloating and gas
Calms inflammation in the intestinal mucosa

Clinical evidence

8-week IBS effectiveness study

n = 52· 8 weeks daily intake

82.5% of patients reported overall improvement.
92% improvement in diarrhoea-dominant IBS subgroup.
Reductions in abdominal cramping, bloating and stool irregularity.
Improved tolerance to previously triggering foods.

Key ingredients at work

L(+) Lactic Acid

Healthy gut pH

Lactobacilli

Probiotic cell-wall support

05 / 08

Detox, Liver & Acidity

Daily toxin load overwhelms your filter system.

Mechanism of action

Phenolic acids (hydroxycinnamic, ellagic) induce phase I & II detox enzymes.
Cynarine from artichokes drives bile flow — the primary route to clear fat-soluble toxins.
Phytochemicals undergo basic (alkaline) metabolism, reversing tissue acidosis at the source.

Phase I + II

Detox pathways activated

How it affects your life

Sluggish mornings, dull skin, puffy eyes
Heavy meals, alcohol, processed food
Reflux, heartburn or acidic stomach
Environmental toxins from city life

How Floradyle helps

Phenolic acids switch on phase I & II detox enzymes
Artichoke and curcuma support bile flow
Reduces acidosis — the body returns to balance
Heartburn and reflux symptoms ease, often within weeks

Clinical evidence

Total Oxidative Status (TOS), randomised intervention

Healthy adults, baseline TOS > 100 µmol/l· 4 weeks daily intake

Floradyle group: TOS dropped −39.5 µmol/l (significant).
Placebo group: TOS dropped only −16.1 µmol/l (not significant).
Greater benefit in those who needed it most — true regulator behaviour.
Intracellular reduced glutathione (master antioxidant) increased significantly.

Key ingredients at work

06 / 08

Skin, Eczema & Aging

Inflammation and oxidative stress age skin from within.

Mechanism of action

Reduces IL-6 and IP-10 — the inflammatory messengers that drive eczema and redness.
Activates proteasomes that clear damaged proteins inside aged keratinocytes.
Raises ATP in skin cells, restoring division capacity that slows with age.

≈ Steroid

Anti-inflammatory power, in vitro

How it affects your life

Dry, itchy patches or eczema flare-ups
Dull tone, fine lines, slow recovery from blemishes
Stress and lack of sleep show on your face
You want results without strong steroid creams

How Floradyle helps

In-vitro: matched dexamethasone in calming skin inflammation
Activates proteasomes — clears damaged proteins in skin cells
Raises ATP in keratinocytes for stronger, springier skin
Can be sprayed topically (1:1 water) on affected areas

Clinical evidence

In vitro atopic-dermatitis & anti-ageing models

Skin epithelial cells + activated T lymphocytes· 24–48 h cell-culture exposure

IP-10 reduced to ~8% of control — better than dexamethasone (~50%).
IL-6 reduction comparable to corticosteroid dexamethasone.
Dose-dependent proteasome activation in artificially aged keratinocytes.
Topical 1:1 spray reported to ease eczema, psoriasis and slow-healing wounds.

Key ingredients at work

Polyphenols

Anti-aging antioxidants

07 / 08

Immunity & Infections

A tired immune system can't tell friend from foe.

Mechanism of action

Activates innate defence (neutrophils, NK cells) without over-stimulating adaptive response.
No IL-4 spike — does not provoke atopy or allergy reactions.
Microbial challenge test: direct antimicrobial action against bacteria and fungi.

NK + Neutrophils

Activated for whole-body defence

How it affects your life

Catching every cold the office passes around
Slow wound healing, lingering skin infections
Allergies, hayfever, food intolerances
Run-down feeling after travel or stress

How Floradyle helps

Activates neutrophils and NK cells (innate defence)
Modulates — not over-stimulates — the immune response
Direct antimicrobial action vs. bacteria & fungi
Raises IL-10 (immune tolerance), no IL-4 spike (no allergy boost)

Clinical evidence

Immunomodulation & microbial challenge

In vitro / ex vivo human cell models· Multiple replicate experiments

IL-10 (immune tolerance) significantly raised.
Probiotic peptidoglycans from lactobacilli cell walls boost mucosal immunity.
Direct kill curves against Candida, S. aureus and other common pathogens.
Reported topical use accelerates wound, abscess and cold-sore healing.

Key ingredients at work

Lactobacilli

Trains the immune system

08 / 08

Inflammation & Joint Pain

Silent inflammation drives pain, stiffness and aging.

Mechanism of action

Polyphenols and curcuminoids quiet IL-6 and IP-10 inflammatory cascades.
Raises intracellular glutathione — the master antioxidant cells use to neutralise ROS.
Reduces oxidative stress more in those with the highest baseline — a regulator, not a stimulant.

↓ IL-6

Inflammatory marker reduced

How it affects your life

Morning stiffness, achy knees or shoulders
Slower recovery after exercise or long days
Background pain that paracetamol only masks
You want relief without daily NSAIDs

How Floradyle helps

Reduces IL-6 and IP-10 — key inflammatory messengers
Raises intracellular glutathione (master antioxidant)
Supports joint comfort, mobility and recovery
Reduces oxidative stress most in those who need it most

Clinical evidence

Intracellular glutathione + cytokine panel

Real-life intervention cohort· 6 months daily intake

Pro-inflammatory IL-6 reduced to dexamethasone-comparable levels in vitro.
Reduced glutathione (GSH) significantly raised in cells.
Almost all patients with chronic inflammation reported clear or complete relief of symptoms.
Joint comfort, mobility and post-exertion recovery improved subjectively.

Key ingredients at work

Shop Floradyle View clinical studies